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Find Faculty / Donald Freytes

Contact Information:

Donald Freytes

4208D Engineering Building III
Campus Box 7115
Raleigh, NC 27695
NC State University
(919) 513-7933,,,

Research Areas:
  • Regenerative Medicine
  • Ph.D. University of Pittsburgh, Pittsburgh, PA.
  • M.S.BME. Purdue University, West Lafayette, IN
  • B.S.ME. Purdue University, West Lafayette, IN


Dr. Freytes’ laboratory focuses on the design and testing of bioengineered tissues mainly composed of pluripotent stem cell-derived repair cells and tissue-specific extracellular matrix scaffolds. The overall goal is to develop new strategies to assemble and test bioengineered constructs capable of restoring tissue function. The major goals of the laboratory are 1) to harness the power of tissue-specific extracellular matrices to guide stem cell differentiation and/or tissue remodeling in vitro and in vivo, and 2) to understand and harness the interaction between inflammatory cells and bioengineered tissue constructs in order to improve incorporation and survival.

Research Interests

Human pluripotent stem cells differentiation
Modeling inflammation and macrophage polarization
Studying interactions between tissue engineered devices and the host tissue response


Young Investigator Travel Award (TERMIS) 2012
Fellow-to-Faculty Award from the New York State Health Department (NYSTEM) 2010

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